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Introduction to EONS v2.0

E.O.N.S. stands for 'Elementary Objects of Neural Systems'. It is an interactive program that allows the modeling of a synapse. E.O.N.S. was designed to provide users with a computational tool to better understand the interactions between elements within the synapse, as well as the influence of its geometry. It was developed by Dr. Jean-Marie Bouteiller (database and database connectivity designed and developed by Yumei Qiu) in the laboratory of Dr. Theodore W. Berger at University of Southern California. It consists of a modeling platform that contains several modules, some of them being already integrated in the main software.

E.O.N.S. is a work in progress. Please, come back often to check on the latest status of your modeling platform and feel free to send us your feedback at jbouteil@usc.edu.

What is E.O.N.S.:

E.O.N.S. is a simulation platform that allows users to create synaptic models. This means that users can litteraly build a virtual synapse from scratch, starting with a few calcium channels, a release site and postsynaptic receptors, and eventually implement more complex mechanisms (second messenger pathways, metabotropic receptors). E.O.N.S. was designed to provide users with a computational tool to better understand the interactions between elements within the synapse, as well as the influence of its geometry.

eons DB - client

From a computational standpoint, E.O.N.S. consists of a Java WebStart application that communicates with a central database in which the models and elements are stored. Users can save and retrieve models and parts of these models.

Structure of E.O.N.S.:

The E.O.N.S. simulation platform contains models, structures, elements, reactions and simulations. Following is a definition of these components, and an explanation of how they interact:



Requirements: 

EONS V2.0 is a Web Start application and requires a Java virtual machine. We recommend the latest version of Java. Please visit the Java website for more information. Check our Help section for more details.

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